ITIH-5 Expression in Human Adipose Tissue Is Increased in Obesity
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چکیده
منابع مشابه
Insulin degradation by adipose tissue is increased in human obesity.
White adipose tissue samples from obese and lean patients were used for the estimation of insulin protease and insulin:glutathione transhydrogenase using 125I-labeled insulin. There was no activity detected in the absence of reduced glutathione, which indicates that insulin is cleaved in human adipose tissue through reduction of the disulfide bridge between the chains. Obese patients showed hig...
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Gokhan S. Hotamisligil, * Peter Arner, Jose F. Caro, Richard L. Atkinson,11 and Bruce M. Spiegelman *Dana Farber Cancer Institute and Department of Cell Biology Harvard Medical School, Boston, Massachusetts 02115; *Karolinska Institute, Department of Medicine Huddinge University Hospital S-141 86 Huddinge, Sweden; 'Jefferson Medical College, Department of Medicine, Philadelphia, Pennsylvania 19...
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ژورنال
عنوان ژورنال: Obesity
سال: 2012
ISSN: 1930-7381
DOI: 10.1038/oby.2011.268